>> SMILES file

SMILES file format description

Many people share .smiles files without attaching instructions on how to use it. Yet it isn’t evident for everyone which program a .smiles file can be edited, converted or printed with. On this page, we try to provide assistance for handling .smiles files.

1 filename extension(s) found in our database.

.smiles - SMILES Chemical Document

The SMILES data files are related to Daylight PCModels. SMILES file is a SMILES Chemical Document. The Simplified Molecular Input Line Entry Specification (SMILES) is a line notation for molecules. SMILES strings include connectivity but do not include 2D or 3D coordinates.

Daylight PCModels
Data files
- / -
SMILES Chemical Document related extensions:
XtraReports Report Definition
Android Call Log Backup
BBEdit Dictionary Data
Dpatch Patch Data
VirtualDub Template
NFE Tools Resource Pack

Naturally, other applications may also use the .smiles file extension. Even harmful programs can create .smiles files. Be especially cautious with .smiles files coming from an unknown source!

Can't open a .smiles file?

When you double-click a file to open it, Windows examines the filename extension. If Windows recognizes the filename extension, it opens the file in the program that is associated with that filename extension. When Windows does not recognize a filename extension, you receive the following message:

Windows can't open this file:


To open this file, Windows needs to know what program you want to use to open it. Windows can go online to look it up automatically, or you can manually select one from a list of programs that are installed on your computer.

To avoid this error, you need to set the file association correctly.

Operating systems currently supports the following operating systems:

Windows XP/Vista, Windows 7/8, Windows 10, CentOS, Debian GNU/Linux, Ubuntu Linux, FreeBSD, Mac OS X, iOS, Android

If you find the information on this page useful, please feel free to link to this page.

If you have useful information about the .smiles file format, then write to us!

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